Isolation and purification of phagocytosis-stimulating factor from neutrophils
نویسندگان
چکیده
منابع مشابه
Identification of precursor of phagocytosis-stimulating factor in guinea pig polymorphonuclear neutrophils.
A precursor of phagocytosis-stimulating factor (PSF) was identified by immunoblot assay with purified anti-PSF antibodies. The purified anti-PSF antibodies recognized not only the PSF with a molecular weight of 16,000 (16K) but also the 36K protein with a pI of 6.5 in the granule fraction of polymorphonuclear neutrophils, indicating that this 36K protein has an antigenic determinant common to P...
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In order to determine whether human granulocyte-macrophage colony-stimulating factor (GM-CSF) can enhance phagocytosis, neutrophils were combined with Staphylococcus aureus (S aureus), and both the number of bacteria per neutrophil and the percent of neutrophils phagocytizing were assessed in the absence and presence of GM-CSF. Exposure to GM-CSF did not enable neutrophils to ingest unopsonized...
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From the time that the inflammatory reaction was first characterized by its cardinal signs of color, rubor, tumor, et dolor, until the studies on phagocytosis by Metchnikoff, it was considered that this reaction by the organism was detrimental to its well being. Metchnikoff (1), however, saw the process of inflammation as a " . . . salutary reaction against some injurious influence." He stated ...
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Granulocyte colony stimulating factor (G-CSF) is well known for its ability to drive the maturation and mobilization of neutrophils. G-CSF also appears to have the potential to activate functions of mature neutrophils, influencing recruitment at sites of inflammation and tissue injury. We investigated the ability of G-CSF to stimulate adhesion of isolated blood neutrophils. G-CSF induced signif...
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ژورنال
عنوان ژورنال: Ensho
سال: 1984
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.4.4_423